LNX1 antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conj µgating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65(By similarity). Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.
Immunogen : ligand of numb-protein X 1
Aliases : LNX, PDZRN2
Observed MW : 70 kDa
Uniprot ID : Q8TBB1
Reactivity : Human, Mouse, Rat
Application : ELISA, WB
Recommended dilution : WB : 1 : 500-1 : 2000
Gene ID : 84708
Research Area : Epigenetics, Metabolism