LMP2 antibody

Volume : 100 µg
Purification : Immunogen affinity purified
Form : liquid
Purity : 95% as determined by SDS-PAGE
Host : Rabbit
Clonality : polyclonal Ab
Clone ID :
Isotype : IgG
Storage : PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background : The proteasome is a m µLticatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed thro µghout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.
Immunogen : proteasome(prosome, macropain) subunit, beta type, 9(large m µLtifunctional peptidase 2)
Aliases : 20S proteasome, beta1i, LMP2, Low molec µLar mass protein 2, Macropain chain 7, Proteasome chain 7, Proteasome subunit beta 1i, Proteasome subunit beta type 9, PSMB6i, PSMB9, RING12
Observed MW : 21-23 kDa
Uniprot ID : P28065
Reactivity : Human, Mouse, Rat
Application : ELISA, WB, IHC, IP, IF
Recommended dilution : WB : 1 : 500-1 : 1000; IP : 1 : 200-1 : 1000; IHC : 1 : 20-1 : 200; IF : 1 : 50-1 : 500
Gene ID : 5698
Research Area : Immunology, Metabolism