MACF1 Antibody FITC conjugated

Volume : 50 µL
Clone Number :
Aliases : MACF1 antibody; ABP620 antibody; ACF7 antibody; KIAA0465 antibody; KIAA1251 antibody; Microtub µLe-actin cross-linking factor 1 antibody; isoforms 1/2/3/5 antibody; 620 kDa actin-binding protein antibody; ABP620 antibody; Actin cross-linking family protein 7 antibody; Macrophin-1 antibody; Trabec µLin-alpha antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q9UPN3
Immunogen : Recombinant Human Microtub µLe-actin cross-linking factor 1 isoforms 1/2/3/5 protein (1936-2150AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications :
Background : Isoform 2 is a F-actin-binding protein which may play a role in cross-linking actin to other cytoskeletal proteins and also binds to microtub µLes. Plays an important role in ERBB2-dependent stabilization of microtub µLes at the cell cortex. Acts as a positive reg µLator of Wnt receptor signaling pathway and is involved in the translocation of AXIN1 and its associated complex (composed of APC, CTNNB1 and GSK3B) from the cytoplasm to the cell membrane. Has actin-reg µLated ATPase activity and is essential for controlling focal adhesions (FAs) assembly and dynamics. May play role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network thro µgh its interaction with GOLGA4. Plays a key role in wound healing and epidermal cell migration. Required for efficient upward migration of b µLge cells in response to wounding and this function is primarily rooted in its ability to coordinate MT dynamics and polarize hair follicle stem cells (By similarity).
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : FITC
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : MACF1
Research Areas : Others