LRRK2 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : a µgmented in rheumatoid arthritis 17 antibody; AURA17 antibody; Dardarin antibody; Leucine rich repeat kinase 2 antibody; leucine rich repeat serine threonine protein kinase 2 antibody; Leucine-rich repeat serine/threonine-protein kinase 2 antibody; LRRK 2 antibody; LRRK2 antibody; LRRK2_HUMAN antibody; PARK 8 antibody; PARK8 antibody; RIPK7 antibody; ROCO 2 antibody; ROCO2 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q5S007
Immunogen : Recombinant Human Leucine-rich repeat serine/threonine-protein kinase 2 protein (2029-2275AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Positively reg µLates autophagy thro µgh a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Reg µLates neuronal process morphology in the intact central nervous system (CNS). Plays a role in synaptic vesicle trafficking. Phosphorylates PRDX3. Has GTPase activity. May play a role in the phosphorylation of proteins central to Parkinson disease.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LRRK2
Research Areas : Neuroscience