LCAT Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : LCAT antibody; LCAT_HUMAN antibody; Lecithin cholesterol acyltransferase antibody; Lecithin-cholesterol acyltransferase antibody; Phosphatidylcholine sterol acyltransferase antibody; Phosphatidylcholine-sterol acyltransferase antibody; Phospholipid cholesterol acyltransferase antibody; Phospholipid-cholesterol acyltransferase antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P04180
Immunogen : Recombinant Human Phosphatidylcholine-sterol acyltransferase protein (25-433AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Central enzyme in the extracell µLar metabolism of plasma lipoproteins. SyntheVolumed mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16 : 0-18 : 2 or 18 : O-18 : 2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1 plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LCAT
Research Areas : Cancer; Cardiovasc µLar; Metabolism; Signal transduction