L1 Antibody

Volume : 50 µg
Clone Number :
Aliases : L1 antibody; Major capsid protein L1 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human) papillomavirus type 16
UniProt ID : P03101
Immunogen : Recombinant Human papillomavirus type 16 Major capsid protein L1 protein (6-471AA)
Raised in : Rabbit
Species Reactivity : Human papillomavirus type 16
Tested Applications : ELISA
Background : Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by dis µLfide bonds and associated with L2 proteins. Binds to heparan s µLfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encaps µLates the genomic DNA together with protein L2.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Non-conj µgated
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : L1
Research Areas : Cancer; Microbiology