LONP1 Antibody HRP conjugated
Volume : 50 µg
Clone Number :
Aliases : hLON antibody; hLON ATP dependent protease antibody; LON antibody; lon peptidase 1 mitochondrial antibody; LON protease antibody; Lon protease homolog antibody; Lon protease like protein antibody; Lon protease-like protein antibody; LONHs antibody; LONM_HUMAN antibody; LONP antibody; Lonp1 antibody; MGC1498 antibody; mitochondrial antibody; Mitochondrial ATP dependent protease Lon antibody; Mitochondrial ATP-dependent protease Lon antibody; Mitochondrial lon peptidase 1 antibody; PIM1 antibody; Protease serine 15 antibody; PRSS15 antibody; Serine protease 15 antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : P36776
Immunogen : Recombinant Human Lon protease homolog, mitochondrial protein (614-959AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived reg µLatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the reg µLation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May reg µLate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of reg µLatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute reg µLatory (StAR) protein.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : LONP1
Research Areas : Epigenetics and Nuclear Signaling; Cancer; Metabolism