KSR2 Antibody HRP conjugated

Volume : 50 µg
Clone Number :
Aliases : FLJ25965 antibody; hKSR 2 antibody; hKSR2 antibody; Kinase suppressor of Ras 2 antibody; KSR 2 antibody; Ksr2 antibody; KSR2_HUMAN antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Homo sapiens (Human)
UniProt ID : Q6VAB6
Immunogen : Recombinant Human Kinase suppressor of Ras 2 protein (159-296AA)
Raised in : Rabbit
Species Reactivity : Human
Tested Applications : ELISA
Background : Location-reg µLated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro). Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro). Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative reg µLator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : HRP
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, pH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : KSR2
Research Areas : Signal transduction