Kng1 Antibody Biotin conjugated

Volume : 50 µg
Clone Number :
Aliases : Kng1 antibody; Kng antibody; Kininogen-1 [Cleaved into : Kininogen-1 heavy chain; Bradykinin; Kininogen-1 light chain] antibody
Product Type : polyclonal Ab Antibody
Immunogen Species : Rattus norvegicus (Rat)
UniProt ID : P08934
Immunogen : Recombinant Rat Kininogen-1 protein (2-110AA)
Raised in : Rabbit
Species Reactivity : Rat
Tested Applications : ELISA
Background : Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coag µLation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects : (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vasc µLar permeability, (4E2) stim µLation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
Clonality : polyclonal Ab
Isotype : IgG
Purification Method : >95%, Protein G purified
Conj µgate : Biotin
Buffer : Preservative : 0.03% Proclin 300
Constituents : 50% Glycerol, 0.01M PBS, PH 7.4
Form : Liquid
Stroage : Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names : Kng1
Research Areas : Others